Kyrie Irving character Uncle Drew
Lil Rel Howery character Dax
Shaquille O'Neal character Big Fella
Chris Webber character Preacher
Reggie Miller character Lights
Nate Robinson character Boots
Lisa Leslie character Betty Lou
Erica Ash character Maya
J.B. Smoove character Angelo
Mike Epps character Louis
Tiffany Haddish character Jess
Nick Kroll character Mookie
William Walker character Golfer
Crystal Lee Brown character Mom
Jamel Chambers character Angry Fan
Terence Rosemore character Customer #1
Ashton Tyler character Young Dax
Aaron Gordon character Casper
Gage Lawson character Teen Playing Basketball (uncredited)
Alannah Wilhite character Girl in club