Johnny Depp character Dr. Will Caster
Rebecca Hall character Evelyn Caster
Paul Bettany character Max Waters
Cillian Murphy character Agent Donald Buchanan
Kate Mara character Bree
Cole Hauser character Colonel Stevens
Morgan Freeman character Joseph Tagger
Clifton Collins Jr. character Martin
Cory Hardrict character Joel Edmund
Falk Hentschel character Bob
Josh Stewart character Paul
Luce Rains character Roger
Fernando Chien character Heng
Steven Liu character Chiu
Xander Berkeley character Dr. Thomas Casey
Lukas Haas character James Thomas
Wallace Langham character Dr. Strauss
James Burnett character Meth Head #1
Sam Quinn character Meth Head #2
Sam Webb character Red Hooded Teenager
Chris Gartin character Tech Conference Coordinator
Olivia Taylor Dudley character Groupie
Abe Martell character RIFT Hacker
Lauren Sivan character Reporter
Laramie Cooley character BDC Greeter
Nancy Jeris character BDC Servant
Colin Jones character FBI Agent
Dylan Kenin character FBI Agent
Chad Brummett character Solar Field Worker
Antonio Del Prete character Will In Hybrid
Jon Kristian Moore character Will In Hybrid
John Trejo character Special Forces on Roof
Darren P. Leis character Medical Lab Tech
Donna Brown character RIFT Surgeon
Richard Daniel Williams character RIFT Surgeon
Zack Carpenter character RIFT Medical Tech
Christina Lancellotti character RIFT Medical Tech
Kristen Rakes character MIT Programmer
Seth Adkins character Miserable Student
Jaime Powers character Hybrid Townsman (uncredited)
Lubella Gauna character Nurse (uncredited)
Lyn Quinn character Tech Conference Attendee (uncredited)
Kendra Tuthill character Townswoman (uncredited)
Darrick Hurst character Berkeley Student (uncredited)
