Dan Aykroyd character Louis Winthorpe III
Eddie Murphy character Billy Ray Valentine
Jamie Lee Curtis character Ophelia
Ralph Bellamy character Randolph Duke
Don Ameche character Mortimer Duke
Denholm Elliott character Coleman
Kristin Holby character Penelope Witherspoon
Paul Gleason character Clarence Beeks
Alfred Drake character President of Exchange
Bo Diddley character Pawnbroker
Frank Oz character Corrupt Cop
Jim Belushi character Harvey
Al Franken character Baggage Handler #1
Tom Davis character Baggage Handler #2
Maurice Woods character Duke & Duke Employee
Richard D. Fisher, Jr. character Duke & Duke Employee
Jim Gallagher character Duke & Duke Employee
Anthony DiSabatino character Duke & Duke Employee
Bonnie Behrend character Duke & Duke Employee
Sunnie Merrill character Duke & Duke Employee
James Newell character Duke & Duke Employee
Mary St. John character Duke & Duke Employee
Bonnie Tremena character Duke & Duke Employee
David Schwartz character Duke & Duke Employee
Tom Degidon character Duke Domestic
William Magerman character Duke Domestic
Alan Dellay character Duke Domestic
Florence Anglin character Duke Domestic
Ray D'Amore character Duke Domestic
Bobra Suiter character Duke Domestic
Herb Peterson character Duke Domestic
Sue Dugan character Duke Domestic
Walt Gorney character Duke Domestic
B. Constance Barry character Duke Domestic
P. Jay Sidney character Heritage Club Doorman
Avon Long character Ezra
Tom Mardirosian character Officer Pantuzzi
Charles Brown character Officer Reynolds
Robert Curtis Brown character Todd
Nicholas Guest character Harry
John Bedford Lloyd character Andrew
Tony Sherer character Philip
Robert Earl Jones character Attendant
Robert E. Lee character Cop #1
Peter Hock character Cop #2
Clint Smith character Doo Rag Lenny
Ron Taylor character Big Black Guy
James D. Turner character Even Bigger Black Guy
Giancarlo Esposito character Cellmate #2
Steve Hofvendahl character Cellmate #3
James Eckhouse character Guard
Gwyllum Evans character President of Heritage Club
Eddie Jones character Cop #3
John McCurry character Cop #4
Michelle Mais character Hooker #1
Barra Khan character Hooker #2
Bill Cobbs character Bartender
Joshua Daniel character Party Goer
Jacques Sandulescu character Creepy Man
W.B. Brydon character Bank Manager
Margaret H. Flynn character Duke & Duke Receptionist
Tracey K. Shaffer character Constance
Susan Fallender character Bunny
Lucianne Buchanan character President's Mistress
Paul Garcia character Jr. Executive #1
Jed Gillin character Jr. Executive #2
Philip Bosco character Doctor
Bill Boggs character Newscaster
Deborah Reagan character Harvey's Girlfriend
Don McLeod character Gorilla
Stephen Stucker character Station Manager
Richard Hunt character Wilson
Paul Austin character Trader #1
John Randolph Jones character Trader #2
Jack Davidson character Trader #3
Bernie McInerney character Trader #4
Maurice Copeland character Secretary of Agriculture
Ralph Clanton character Official #1
Bryan Clark character Official #2
Gary Klar character Longshoreman
Afemo Omilami character Longshoreman
Shelly Chee Chee Hall character Monica
Donna Palmer character Gladys
Barry Dennen character Demitri
Murray Bandel character Man at Police Station (uncredited)
Peter Fey character (uncredited)
George Folsey Jr. character (uncredited)
John Landis character Man with Briefcase (uncredited)
Shirley Levine character Bag Lady (uncredited)
Charles Pendelton character Cop (uncredited)
Yvonna Russell character Girl in Park (uncredited)
Arleen Sorkin character Woman at Party (uncredited)
Ronald Sylvers character Rolls Royce Driver (uncredited)
Marlene Willoughby character Woman Passed out on Couch (uncredited)
Kelly Curtis character Muffy
