Rose Byrne character Rebecca Skloot
Renée Elise Goldsberry character Henrietta Lacks
Oprah Winfrey character Deborah Lacks
Ninja N. Devoe character Country Girl Mae
Lisa Arrindell character Aunt Ethel
Earl Poitier character Cousin Josh
L. Warren Young character Day Lacks
Patrick R. Walker character Cousin Fred
Jane Rumbaua character Mrs. Hsu
Sylvia Grace Crim character Mary Kubicek
Tian Richards character Lawrence (16 yrs.)
Kate Bond character Young Woman
Jazzy Ellis character Young Gladys
Jock McKissic character Carl the Mechanic
Kyanna Simone Simpson character Deborah (15-24YRS)
Tinashe Kajese character Sadie
Kayla Anderson character Johns Hopkins Student
Karen Wheeling Reynolds character Mrs. Gey
Todd Lee character Doctor
Jordan Eli Arellano character Young Sonny Lacks
Mary Shaw character Woman at Pump
Tatom Pender character Johns Hopkins Nurse
Christopher Robert Escobar character Chris the Intern
Clint Edwards character Scientist
De'Marco Arrington character Young Joe
Jaylon Gordon character Alfred
Tashaun Stanfill-Perry character Henrietta Lacks Neighbor
Matthew Bernard character Johns Hopkins Student
Sage Mayer character Young Boy
Elizabeth Hackler character Rebecca's Co-worker
David Shae character Reporter
Jaedon Godley character Davon Lacks
Tyvonna Jones character Elsie Lacks
Raphael Dante' Carr Jr. character Young Sonny
Miguel Angel Marrero character Scientist
Courtney B. Vance character Sir Lord Keenan Coefield
Reed Birney character Dr. George Gey
Alpha Trivette character First Administrator
Terrence V. Walker character Church Patron
Sean Freeland character Charlie
Reg E. Cathey character Zakariyyah
William Walker character Hospital Utility Worker (uncredited)
Gabriel Ebert character Christoph Lengauer