Kumail Nanjiani character Kumail Nanjiani
Zoe Kazan character Emily Gardner
Holly Hunter character Beth Gardner
Ray Romano character Terry Gardner
Anupam Kher character Azmat Nanjiani
Zenobia Shroff character Sharmeen Nanjiani
Adeel Akhtar character Naveed Nanjiani
Bo Burnham character CJ
Aidy Bryant character Mary
Kurt Braunohler character Chris
Vella Lovell character Khadija
Myra Lucretia Taylor character Nurse Judy
Jeremy Shamos character Bob Dalavan
David Alan Grier character Andy Dodd
Ed Herbstman character Sam Highsmith
Shenaz Treasury character Fatima Nanjiani
Rebecca Naomi Jones character Jesse
Kuhoo Verma character Zubeida
Mitra Jouhari character Yazmin
Celeste Arias character Denise
Shana Solomon character Nurse Bette
Jeff Blumenkrantz character Dr. Wright
Linda Emond character Dr. Cunningham
Holly Chou character Dr. Whelan
Andrew Pang character Dr. Spellman
Alison Cimmet character Dr. Platt
Lawrence Ballard character Dr. Lewin
Shunori Ramanathan character Sumera
Spencer House character Racist Heckler
Susham Bedi character Tina (Khadija's Mother)
Rahul Bedi character Farhan (Khadija's Father)
Matthew Cardarople character Fast Food Cashier
Myra Turley character Waiting Room Person 1
William Stephenson character Waiting Room Person 2
Marilyn Torres character Waiting Room Person 3
Kerry Flanagan character Waiting Room Person 4
Jack O'Connell character Waiting Room Person 5
Charles Gould character Waiting Room Person 6
Isabel Shill character Party Goer 1
Lauren Patten character Party Goer 2
Keilly McQuail character Party Goer 3
Zach Cherry character Party Goer 4
Jack Corrigan character Restaurant Boy (uncredited)
Sophia Muller character Chrissy (uncredited)