Annabelle Wallis character Madison Mitchell / Emily May
Maddie Hasson character Sydney Lake
George Young character Detective Kekoa Shaw
Michole Briana White character Detective Regina Moss
Mckenna Grace character Young Madison Mitchell / Emily May
Jacqueline McKenzie character Dr. Florence Weaver
Jake Abel character Derek Mitchell
Ray Chase character Gabriel (voice)
Jean Louisa Kelly character Jane Doe / Serena
Susanna Thompson character Jeanne
Ingrid Bisu character Winnie
Zoë Bell character Scorpion
Marina Mazepa character Gabriel
Christian Clemenson character Dr. Victor Fields
Madison Wolfe character Young Serena
Jon Lee Brody character Officer Lee
Paula Marshall character Beverly Woods
Patrick Cox character Mr. Stanley
Rachel Winfree character Mrs. Ryerson
Paul Mabon character Orderly
Amir Aboulela character Dr. Gregory
Ruben Pla character Officer Rubin
Patricia Velásquez character Nurse Velasquez
Mike Mendez character Hospital Security Guard #1
Renee Harbek character Caroline
Gino Montesinos character Seattle Police Officer
Kalina Vanska character Seattle Police Officer
Gregory Garcia character Seattle Police Officer
Andy Bean character Frank
Christina Veronica character Holding Cell Inmate (uncredited)
Janet Hsieh character Nurse J. De Marco (uncredited)
Halston Van Atta character Child Madison (uncredited)
Louise Van Veenendaal character Prisoner (uncredited)
Radhesh Aria character Hospital Doctor
