John Wayne character Capt. Nathan Cutting Brittles
Joanne Dru character Olivia Dandridge
John Agar character Lt. Flint Cohill
Ben Johnson character Sgt. Tyree
Harry Carey, Jr. character 2nd Lt. Ross Pennell
Victor McLaglen character First Sergeant Quincannon
Mildred Natwick character Abby Allshard ("Old Iron Pants")
George O’Brien character Maj. Mac Allshard
Arthur Shields character Dr. O'Laughlin
Michael Dugan character Sgt. Hochbauer
Chief John Big Tree character Chief Pony That Walks
Fred Graham character Sgt. Hench
George Sky Eagle character Chief Sky Eagle
Tom Tyler character Cpl. Mike Quayne
Noble Johnson character Chief Red Shirt
Paul Fix character Gunrunner (uncredited)
Francis Ford character Connelly - Fort Stark Suttlers Barman (uncredited)
Cliff Lyons character Trooper Cliff (uncredited)
Frank McGrath character Bugler / Indian (uncredited)
Irving Pichel character Narrator (voice) (uncredited)
William Steele character Officer (uncredited)
Jack Tornek character Officer (uncredited)
Dan White character Trooper (uncredited)
Harry Woods character Karl Rynders (uncredited)