Seth Rogen character Frank / Sergeant Pepper (voice)
Kristen Wiig character Brenda (voice)
Jonah Hill character Carl (voice)
Bill Hader character Firewater / Tequila / El Guaco (voice)
Michael Cera character Barry (voice)
James Franco character Druggie (voice)
Danny McBride character Honey Mustard (voice)
Craig Robinson character Grits (voice)
Paul Rudd character Darren (voice)
Nick Kroll character Douche (voice)
David Krumholtz character Lavash (voice)
Edward Norton character Sammy Bagel Jr. (voice)
Salma Hayek character Teresa Taco (voice)
Anders Holm character Troy (voice)
Scott Underwood character Gum / Twink / Krinkler's Chips / Pizza (voice)
Sugar Lyn Beard character Baby Carrot / Cookies (voice)
Conrad Vernon character Toilet Paper / Sauerkraut / Catcall Sausage / Grape #1 / Beer Can / Pop Bottle (voice)
Ian James Corlett character Apple / Tickilish Licorice / Relish / Bag of Dog Food (voice)
Michael Daingerfield character Chunk Munchers Cereal / Light Bulb / Indian Chutney (voice)
Jason Simpson character Plum #2 / Beer Keg / Fat Guy / Fit Man (voice)
Vincent Tong character Pislitz Chips / Juice Box / Jamaican Rum (voice)
Karen E. Wright character Diner Waitress
Lauren Miller character Camille Toh / Tampon (voice)
Sam Vincent character Old Pork Sausage / Refried Beans / Sandwich / Pop Tart / Licorice Rope (voice)
Greg Tiernan character Potato / Noodle Soup (voice)
Brian Dobson character Italian Tomato / Lettuce (voice)
Harland Williams character Ketchup / Drug Dealer / Baba Ganoush (voice)
Alistair Abell character Mariachi Salsa / Gefilte Fish (voice)
Iris Apatow character Berry Good Candies / Grape #3 / Coconut Milk (voice)
Michael Dobson character Queso (voice)
Ian Hanlin character Beet (voice)
Maryke Hendrikse character Popped Cherry Mixer / Plum #1 / Loretta Bun / Frozen Fruitz (voice)
Nicole Oliver character Sally Bun / Ice Cream / Watermelon / Female Shopper #1 (voice)
Kelly Sheridan character Roberta Bun / Grape #2 / Female Shopper #2 (voice)