James Badge Dale character Robert Oswald
Zac Efron character Jim Carrico
Jackie Earle Haley character Father Oscar Huber
Colin Hanks character Dr. Malcom Perry
David Harbour character Gordon Shanklin
Marcia Gay Harden character Doris Nelson
Ron Livingston character James Hosty
Jeremy Strong character Lee Harvey Oswald
Billy Bob Thornton character Forrest Sorrels
Jacki Weaver character Marguerite Oswald
Tom Welling character Roy Kellerman
Paul Giamatti character Abraham Zapruder
Paul Sparks character Harry McCormick
Mark Duplass character Kenneth O'Donnell
Rory Cochrane character Earl Rose
Austin Nichols character Emory Roberts
Elizabeth Tulloch character Marilyn Sitzman
Dana Wheeler-Nicholson character Lillian Zapruder
Gil Bellows character David Powers
Kat Steffens character Jacqueline Kennedy
Brett Stimely character President Kennedy
Sean McGraw character Lyndon B. Johnson
Jimmie Dale Gilmore character Reverend Saunders
Matt Barr character Paul Mikkelson
Jonathan Breck character Winston Lawson
Gary Grubbs character Dr. Kemp Clark
Bryan Batt character Malcolm Kilduff
Glenn Morshower character Mike Howard
Gary Clarke character Admiral George Burkley
Mallory Moye character Emergency Room Nurse
Jason Douglas character Ken Howe
Larry Jack Dotson character Acme Brick Supervisor
Nico Evers-Swindell character Rufus Youngblood
Irene White character Hospital Switchboard Operator #1
Luci Christian character Hospital Switchboard Operator #2
Ellen Halper character Acme Brick Timekeeper
Chris Freihofer character Chamberlain
Taylor Scorse character Nurse
Oryan Landa character Texas Ranger
Heath Allyn character Secret Service Agent (uncredited)
Sarah Joy Byington character Marina Oswald (uncredited)
John Cann character Secret Service Agent (uncredited)
Anthony J. Caruso character Secret Service Agent (uncredited)
Darryl Cox character Gen. Godfrey McHugh (uncredited)
Armando Gutiérrez character Dallas Police Officer - Glen McBride (uncredited)
Nathaniel Holt character Acme Brick Employee (uncredited)
Anne Lockhart character ER Nurse (uncredited)
Greg Wise character Doctor in Trauma Room (uncredited)