Basil Rathbone character Sherlock Holmes
Nigel Bruce character Dr. John H. Watson
Alan Mowbray character Major Duncan-Bleek
Dennis Hoey character Inspector Lestrade
Renee Godfrey character Vivian Vedder
Frederick Worlock character Prof. William Kilbane
Mary Forbes character Lady Margaret Carstairs
Skelton Knaggs character Sands - Moran's Accomplice
Billy Bevan character Conductor Taking Tickets
Geoffrey Steele character Roland Carstairs
Jane Murdoch character Mrs. Shallcross (uncredited)
Gerald Hamer character Alf Shallcross (uncredited)
Leland Hodgson character Senior Conductor (uncredited)
Harry Cording character Mock the Undertaker (uncredited)
Charles Knight character Baggage Car Guard (uncredited)
Boyd Davis character "Inspector MacDonald" (uncredited)
Bobby Wissler character Mock Jr. (uncredited)
Gilbert Allen character Dining Car Steward (uncredited)
C. Aubrey Smith character Elderly gentleman on train station (uncredited)
