Michael J. Fox character Stuart Little (voice)
Geena Davis character Mrs. Eleanor Little
Hugh Laurie character Mr. Fredrick Little
Jonathan Lipnicki character George Little
Nathan Lane character Snowbell (voice)
Steve Zahn character Monty (voice)
Chazz Palminteri character Smokey (voice)
David Alan Grier character Red (voice)
Jennifer Tilly character Camille Stout (voice)
Jim Doughan character Det. Phil Allen / Lucky (voice)
Bruno Kirby character Reginald Stout (voice)
Stan Freberg character Race Announcer (voice)
Jeffrey Jones character Crenshaw Little
Connie Ray character Tina Little
Allyce Beasley character Beatrice Little
Brian Doyle-Murray character Edgar Little
Estelle Getty character Estelle Little
Harold Gould character Spencer Little
Patrick Thomas O'Brien character Uncle Stretch
Julia Sweeney character Mrs. Keeper
Dabney Coleman character Dr. Beechwood
Miles Marsico character Anton
Jon Polito character Detective Sherman
Joe Bays character Race Starter
Taylor Negron character Salesman in Mall
Kimmy Robertson character Race Spectator
Tannis Benedict character Hot Dog Vendor
