Tom Hanks character Sam Baldwin
Meg Ryan character Annie Reed
Ross Malinger character Jonah Baldwin
Rita Wilson character Suzy
Victor Garber character Greg
Tom Riis Farrell character Rob
Carey Lowell character Maggie Baldwin
Bill Pullman character Walter
Le Clanché du Rand character Barbara Reed
Kevin O'Morrison character Cliff Reed
David Hyde Pierce character Dennis Reed
Valerie Wright character Betsy Reed
Frances Conroy character Irene Reed
Tom Tammi character Harold Reed
Calvin Trillin character Uncle Milton
Caroline Aaron character Dr. Marcia Fieldstone
Linda Wallem character Loretta
LaTanya Richardson Jackson character Harriet
Rosie O'Donnell character Becky
Tom McGowan character Keith
Steve Mellor character Wyatt
Marguerite Schertle character Baltimore Waitress
Dana Ivey character Claire
Brian McConnachie character Bob
Rob Reiner character Jay
Gaby Hoffmann character Jessica
Matt Smith character Mailman
Amanda Maher character Clarise
Barbara Garrick character Victoria
Victor Morris character Seattle Maitre D'
Philip Mihalski character Seattle Waiter
Donald J. Lee Jr. character Seattle Detective
Mary A. Kelly character Nervous Woman on Airplane
Diane Sokolow character Tiffany Saleswoman
Hannah Cox character Jessica's Mother
Rich Hawkins character Jessica's Father
Tamara Plank character Stewardess
Michael Badalucco character New York Taxi Dispatcher
Jeff Mazzola character New York Taxi Dispatcher
Philip Levy character Taxi Driver
Julie Janney character Cynthia
Tony Zazula character Maitre D'
John Boylan character Elevator Man
Robert Livingston character Elevator Man
Butch Stevenson character Valet
Sidney Armus character Information Booth Man
Philip Anagnos character Car Driver (uncredited)
Jason Bortz character Baltimore Mail Clerk (uncredited)
Scott Duthie character Tourist (uncredited)
Robert Minkoff character Bit (uncredited)
Roger Petan character Seattle Airport passenger / Seattle diner (uncredited)
William Rossman character Driver (uncredited)
Nick Taylor character Bartender (uncredited)
