Susan Sarandon character Michaela Odone
Nick Nolte character Augusto Odone
Peter Ustinov character Professor Nikolais
Ann Hearn character Loretta Muscatine
Maduka Steady character Omuori
Aaron Jackson character Francesco Odone
Laura Linney character Young Teacher
Kathleen Wilhoite character Deirdre Murphy
Gerry Bamman character Doctor Judalon
Margo Martindale character Wendy Gimble
James Rebhorn character Ellard Muscatine
Colin Ward character Jake Gimble
LaTanya Richardson Jackson character Nurse Ruth
Jennifer Dundas character Nurse Nancy Jo
William Cameron character Pellerman
Becky Ann Baker character Pellerman's Secretary
Mary Pat Gleason character The Librarian
David Shiner character Clown
Ann Dowd character Pediatrician
Peter MacKenzie character Immunosuppression Doctor
Paul Lazar character Professor Duncan
Joyce Reehling character Columnist
Michael O'Neill character School Psychologist
Richard Cordery character Suddaby's Senior Manager
Angus Barnett character Suddaby's Junior Manager
Elizabeth Daily character Lorenzo Odone (voice)
Zack O'Malley Greenburg character Lorenzo Odone
Sandy Gore character Murphy Family
Nora Dunfee character Murphy Family
Rocco Sisto character Murphy Family
Amelia Campbell character Murphy Family
Keith Reddin character Murphy Family