Chris Pratt character Peter Quill / Star-Lord
Zoe Saldana character Gamora
Dave Bautista character Drax the Destroyer
Vin Diesel character Baby Groot (voice)
Bradley Cooper character Rocket (voice)
Michael Rooker character Yondu Udonta
Karen Gillan character Nebula
Pom Klementieff character Mantis
Sylvester Stallone character Stakar Ogord
Kurt Russell character Ego
Elizabeth Debicki character Ayesha
Chris Sullivan character Taserface
Sean Gunn character Kraglin / On-Set Rocket / On-Set Adolescent Groot
Tommy Flanagan character Tullk
Laura Haddock character Meredith Quill
Aaron Schwartz character Young Ego Facial Reference
Hannah Gottesman character Sovereign Chambermaid
Hilty Bowen character Sovereign Pilot
Ben Browder character Sovereign Admiral
Alexander Klein character Zylak (as Alex Klein)
Luke Cook character Zylak's Frenemy
Evan Jones character Retch
Joe Fria character Oblo
Terence Rosemore character Narblik
Jimmy Urine character Half-Nut
Stephen Blackehart character Brahl
Steve Agee character Gef
Blondy Baruti character Huhtar
Richard Christy character "Down There!"
Rob Zombie character Unseen Ravager
Sierra Love character Robot Courtesan
Kendra Carelli character Robot Courtesan (as Kendra Staub)
Milynn Sarley character Robot Courtesan
Seth Green character Howard the Duck (voice)
Molly C. Quinn character Howard's Date (as Molly Quinn)
Michael Rosenbaum character Martinex
Rhoda Griffis character Sneeper Madame
Stan Lee character Watcher Informant
David Hasselhoff character The Form of David Hasselhoff
Mac Wells character Officer Fitzgibbon
Jim Gunn Sr. character Weird Old Man (as James Gunn, Sr.)
Leota Gunn character Weird Old Man's Mistress
Elizabeth Faith Ludlow character Easik Mother
Wyatt Oleff character Young Peter Quill
Gregg Henry character Grandpa Quill
Damita Jane Howard character Grandpa Quill's Friend
Ving Rhames character Charlie-27
Michelle Yeoh character Aleta Ogord
Fred character Cosmo the Space Dog (uncredited)
Miley Cyrus character Mainframe (voice) (uncredited)
Jeff Goldblum character En Dwi Gast / Grandmaster (uncredited)
Mike Escamilla character Scrote
Donny Carrington character Kree Monk (uncredited)
Brian Clackley character Alien (uncredited)
Nea Dune character Lovebot (uncredited)
Fred Galle character Sovereign Leader (uncredited)
Alphonso A'Qen-Aten Jackson character Ravager (uncredited)
Kelly Richardson character Daisy Kiu (uncredited)
Guillermo Rodriguez character Cop #2 (uncredited)
Josh Tipis character Humanoid Ravager (uncredited)
Jason Williams character Huge Guard of the Sovereign Nation (uncredited)
Cheyanna Lavon Zubas character Robot Courtesan (uncredited)