Sam Rockwell character Darwin the Guinea Pig (voice)
Penélope Cruz character Juarez the Guinea Pig (voice)
Tracy Morgan character Blaster the Guinea Pig (voice)
Jon Favreau character Hurley the Guinea Pig (voice)
Steve Buscemi character Bucky the Hamster (voice)
Nicolas Cage character Speckles the Mole (voice)
Edwin Louis character Mooch the Fly (voice)
Jared Lavette character Jared the Skunk (voice)
Micah Lavette character Micah the Fox (voice)
Bill Nighy character Leonard Saber
Will Arnett character Kip Killian
Zach Galifianakis character Ben
Kelli Garner character Marcie
Niecy Nash character Rosalita
Loudon Wainwright III character Grandpa Goodman
Tyler Patrick Jones character Connor
Piper Mackenzie Harris character Penny
Chris Ellis character NSA Director
Gabriel Casseus character Carter
Justin Mentell character Terrell
Troy Robinson character Agent
Travis Davis character Agent
James Huang character Agent
Corey Michael Eubanks character Agent
Mini Anden character Saber's Assistant
Camaron Engels character Skateboarder #1 (as Cameron Engels)
