Owen Wilson character Reggie (voice)
Woody Harrelson character Jake (voice)
Amy Poehler character Jenny (voice)
George Takei character S.T.E.V.E. (voice)
Colm Meaney character Myles Standish (voice)
Keith David character Chief Broadbeak (Voice)
Dan Fogler character Governor William Bradford (voice)
Lesley Nicol character Female Pilgrim (voice)
Jimmy Hayward character President of the United States/Ranger/Leatherbeak/Hazmats (voice)
Kaitlyn Maher character President's Daughter (voice)
Carlos Alazraqui character Amos (voice)
Josh Lawson character Gus (Voice)
Dwight Howard character Cold Turkey (Voice)
Danny Carey character Danny (voice)
Carlos Ponce character Narrator/Alejandro (voice)
Robert Beltran character Chief Massasoit (voice)
Scott Mosier character Pizza Dude (voice)
