Jerry Seinfeld character Barry B. Benson (voice)
Renée Zellweger character Vanessa Bloome (voice)
Jim Cummings character Narrator / Graduation Announcer (voice)
Matthew Broderick character Adam Flayman (voice)
Patrick Warburton character Ken (voice)
John Goodman character Layton T. Montgomery (voice)
Chris Rock character Mooseblood (voice)
Kathy Bates character Janet Benson (voice)
Barry Levinson character Martin Benson (voice)
Megan Mullally character Trudy (voice)
Rip Torn character Lou Lo Duca (voice)
Oprah Winfrey character Judge Bumbleton (voice)
Michael Richards character Bud Ditchwater (voice)
Larry King character Bee Larry King (voice)
Larry Miller character Buzzwell (voice)
David Moses Pimentel character Hector (voice)
Chuck Martin character Andy (voice)
Brian Hopkins character Sandy Shrimpkin / TSA Agent (voice)
John DiMaggio character Janitor / Bailiff (voice)
Tress MacNeille character Jeanette Chung / Mother / Cow (voice)
Simon J. Smith character Truck Driver / Chet (voice)
Ray Liotta character Himself (voice)
Sting character Himself (voice)
Robert Jayne character Bee (voice) (uncredited)
Carl Kasell character Himself (voice) (uncredited)