Robert De Niro character Leonard Lowe
Robin Williams character Malcolm Sayer
John Heard character Dr. Kaufman
Julie Kavner character Eleanor Costello
Penelope Ann Miller character Paula
Ruth Nelson character Mrs. Lowe
Max von Sydow character Peter Ingham
Anne Meara character Miriam
Dexter Gordon character Rolando
George Martin character Frank
Alice Drummond character Lucy Fishman
Richard Libertini character Sidney
Laura Esterman character Lolly
Barton Heyman character Bert
Judith Malina character Rose
Mary Alice character Nurse Margaret
Keith Diamond character Anthony
Bradley Whitford character Dr. Tyler
John Christopher Jones character Dr. Sullivan
Mary Catherine Wright character Nurse Beth
Jayne Haynes character Frances
Le Clanché du Rand character Magda
Yusef Bulos character Joseph
Steven Randazzo character Luis
Gloria Harper character Dottie
Gwyllum Evans character Desmond
Steve Vinovich character Ray
Tiger Haynes character Janitor
Harvey Miller character Hospital Director
Tanya Berezin character Psychiatrist
Peter Stormare character Neurochemist
Shane Fistell character Man in Hall
Waheedah Ahmad character Hysterical Woman
Charles Keating character Mr. Kean
Christina Huertes character Christina
Linda Burns character Fishsticks
Judy Jacksina character Hospital Receptionist
Gary Tacon character George
Rico Elias character Orderly #1
Mel Gorham character Nurse Sara
Chris Carolan character EEG Technician
Debra Kovner-Zaks character Cafeteria Nurse
Vin Diesel character Hospital Orderly (Uncredited)
Max Rabinowitz character Ward #5 Orderly
Gordon Joseph Weiss character Ward #5 Patient
Byron Utley character Ward #5 Patient #2
Anthony McGowen character Ward #5 Patient #3
Paul Montgomery character Ward #5 Patient #4
Leonard Tepper character Ward #5 Patient #5
Vincent Pastore character Ward #5 Patient #6
Howard Feller character Ward #5 Patient #7
Libby Titus character Club Singer
Michael Hyde character Bus Driver
Tomislav Novakovic character Bartender
Adam Bryant character Librarian
Anthony J. Nici character Young Leonard
Oliver Block character Leonard's Friend #1
Buck Smith character Leonard's Friend #2
Joan E. MacIntosh character Teacher
Harry L. Seddon character Medical Student
