John Wayne character Robert Marmaduke Hightower
Pedro Armendáriz character Pedro 'Pete' Roca Fuerte
Harry Carey, Jr. character William Kearney ('The Abilene Kid')
Ward Bond character Perley 'Buck' Sweet
Mae Marsh character Mrs. Perley Sweet
Mildred Natwick character The Mother
Jane Darwell character Miss Florie
Guy Kibbee character Judge
Dorothy Ford character Ruby Latham
Ben Johnson character Posse man #1
Charles Halton character Oliver Latham
Hank Worden character Deputy Curly
Jack Pennick character Luke
Fred Libby character Deputy
Michael Dugan character Posse Man #2
Don Summers character Posse Man #3
Gertrude Astor character Saloon Girl (uncredited)
Richard Hageman character Saloon Pianist (uncredited)
Nora Bush character Townswoman (uncredited)
Eva Novak character Townswoman (uncredited)
Charles Soldani character Townsman (uncredited)
Ruth Clifford character Woman in Bar (uncredited)
Jack Curtis character Bartender (uncredited)
Harry Tenbrook character Bartender (uncredited)
Tex Driscoll character Barfly (uncredited)
Jack Kenny character Barfly (uncredited)
Jack Mower character Barfly (uncredited)
Francis Ford character Drunk (uncredited)
Cliff Lyons character Guard at Mojave Tanks (uncredited)
Amelia Yelda character Robert William Pedro Hightower (the Baby) (uncredited)