Ben Stiller character Alex (voice)
Jada Pinkett Smith character Gloria (voice)
David Schwimmer character Melman (voice)
Chris Rock character Marty / Additional Zebras (voice)
Cedric the Entertainer character Maurice (voice)
Andy Richter character Mort (voice)
Bernie Mac character Zuba (voice)
Alec Baldwin character Makunga (voice)
Sacha Baron Cohen character Julien (voice)
Sherri Shepherd character Mom (voice)
Will.i.am character Moto Moto (voice)
Elisa Gabrielli character Nana (voice)
Tom McGrath character Skipper / Lemur (voice)
Chris Miller character Kowalski (voice)
Christopher Knights character Private (voice)
Conrad Vernon character Mason (voice)
Quinn Dempsey Stiller character Baby Alex (voice)
Declan Swift character Baby Alex (voice)
Fred Tatasciore character Teetsi / Poacher #1 / Elephant (voice)
Eric Darnell character Joe the Witch Doctor / Poacher #2 (voice)
Willow Smith character Baby Glorida (voice)
Thomas Stanley character Baby Marty (voice)
Zachary Gordon character Baby Melman (voice)
Meredith Vieira character Newscaster (voice)
Lesley Stahl character Newscaster (voice)
Al Roker character Newscaster (voice)
David Soren character Lemur (voice)
Phil LaMarr character Guide (voice)
Stephen Kearin character Stephen the Giraffe / Tourist with Video Camera / Rhino (voice)
Dan O'Connor character Tourist with University Shirt / Cape Buffalo (voice)
Edie Mirman character Telephone Recording (voice)
Fergie character Hippo Girlfriend (voice)
Harland Williams character Additional Giraffe (voice)
Danny Jacobs character Tourist with New York T-Shirt (voice)
Bridget Hoffman character Female Tourist (voice)
Terrence Hardy Jr. character Cub (voice)
Conner Rayburn character Little Giraffe (voice)
Holly Dorff character Fish (voice)
David P. Smith character Bobby the Dik Dik (voice)
Lynnanne Zager character Lioness (voice)
Jackie Gonneau character Additional Dik Dik (voice)
John Eric Bentley character Additional Dialogue (voice)
John DiMaggio character Rico (voice)
