Jack Nicholson character Melvin Udall
Helen Hunt character Carol Connelly
Greg Kinnear character Simon Bishop
Cuba Gooding Jr. character Frank Sachs
Skeet Ulrich character Vincent Lopiano
Shirley Knight character Beverly Connelly
Yeardley Smith character Jackie Simpson
Lupe Ontiveros character Nora Manning
Lawrence Kasdan character Dr. Green
Harold Ramis character Dr. Bettes
Kathryn Morris character Psychiatric Patient
Alison Rose character Psychiatric Patient
Maya Rudolph character Policewoman
Julie Benz character Receptionist
Jimmy Workman character Sean from the Bakery
Jamie Kennedy character Street Hustler
Brian Doyle-Murray character Handyman
Peter Jacobson character Man at Table
Jesse James character Spencer Connelly
Randall Batinkoff character Carol's date
Linda Gehringer character Publisher
Kaitlin Hopkins character Woman in Lobby
Lisa Edelstein character Woman at Table
Danielle Brisebois character Singer
Todd Solondz character Man on Bus
Matt Malloy character Men's Store Salesman
Tom McGowan character Maitre D'
Bibi Osterwald character Neighbor Woman
Ross Bleckner character Carl
Bernadette Balagtas character Caterer
Jaffe Cohen character Partygoer
Laurie Kilpatrick character Partygoer
Alice Vaughn character Partygoer
Shane Black character Cafe 24 Manager
Stan Bly character Cafe 24 Customer
Missi Pyle character Cafe 24 Waitress
Tara Subkoff character Cafe 24 Waitress
Rebekah Johnson character Cafe 24 Waitress
Leslie Stefanson character Cafe 24 Waitress
Patricia Childress character Cafe 24 Waitress
Wood Harris character Cafe 24 Busboy
Chloe Brooks character Child at Cafe 24
Cooper Brooks character Child at Cafe 24
Kristi Zea character Mother at Table
Justin Herwick character Street Hustler
John F. O'Donohue character Detective Ray
Mary Elizabeth Still character Nurse Receptionist
Paul Greenberg character Bar Waiter
David A. Kipper character Hospital Doctor
Antonia Jones character Nurse
Alex Ballar character Flower Store Customer (uncredited)
Bronwyn Cornelius character Bartender (uncredited)
Amy Anzel character Ballet Dancer (uncredited)
Laura Mayes Byrnes character Restaurant Patron (uncredited)
Maurice LaMarche character Fred Bishop - Simon's Dad on Phone (voice) (uncredited)