Ray Romano character Manny (voice)
John Leguizamo character Sid (voice)
Denis Leary character Diego (voice)
Goran Visnjic character Soto (voice)
Jack Black character Zeke (voice)
Cedric the Entertainer character Carl (voice)
Stephen Root character Frank / Start (voice)
Diedrich Bader character Oscar (voice)
Alan Tudyk character Lenny / Oscar / Dab (voice)
Lorri Bagley character Jennifer (voice)
Jane Krakowski character Rachel (voice)
Peter Ackerman character Dodo / Macrauchenia (voice)
P.J. Benjamin character Dodo (voice)
Josh Hamilton character Dodo / Aardvark (voice)
Chris Wedge character Dodo / Scrat (voice)
Denny Dillon character Glyptodon (voice)
Mitzi McCall character Glyptodont (voice)
Tara Strong character Baby Moeritherium (voice)
Darin De Paul character Additional Voices (voice) (uncredited)
Dann Fink character Dodo (voice) (uncredited)
Patrick Pinney character Various Mammals (uncredited)
Phil Proctor character Various Mammals (uncredited)
