Tim Allen character Eliot Arnold
Rene Russo character Anna Herk
Patrick Warburton character Officer Walter Kramitz
Ben Foster character Matt Arnold
Zooey Deschanel character Jenny Herk
Stanley Tucci character Arthur Herk
Tom Sizemore character Snake Dupree
Johnny Knoxville character Eddie Leadbetter
Dennis Farina character Henry Desalvo
Jack Kehler character Leonard Ferroni
Janeane Garofalo character Officer Monica Romero
Heavy D character FBI Agent Pat Greer
Omar Epps character FBI Agent Alan Seitz
Jason Lee character Puggy
Sofía Vergara character Nina
Michael McShane character Bruce
Siobhan Fallon Hogan character Fly by Air Ticket Agent
Lars Arentz-Hansen character Leo
Jay Rasumny character Courier #1
Andy Richter character Jack Pendick / Ralph Pendick
Daniel London character John / Ivan
DJ Qualls character Andrew
Cullen Douglas character Fly by Air Captain Justin Hobart
Flip Schultz character Fly by Air Co-Pilot Jan Vigushin
Jonathan Kasdan character Jack Pendick Trainee
Ian Marioles character Editorial Assistant
Philip Nolen character Ken Deeber, Miami Herald Editor
David Koepp character Annoyed Sports Radio Host (voice)
Barry Sonnenfeld character Confused Sports Radio Call In (voice)
Antoni Corone character William Spaulding
Kava Stewartson character Sour Airport Security
Marc Macaulay character Airport Officer Arch Ridley
Deborah Smith Ford character Bag Lady (uncredited)
