John Wayne character Capt. Kirby York
Henry Fonda character Lt. Col. Owen Thursday
Shirley Temple character Philadelphia Thursday
Pedro Armendáriz character Sgt. Beaufort
Ward Bond character Sgt. Maj. Michael O'Rourke
George O’Brien character Capt. Sam Collingwood
Victor McLaglen character Sgt. Festus Mulcahy
Anna Lee character Mrs. Emily Collingwood
Irene Rich character Mrs. Mary O'Rourke
Dick Foran character Sgt. Quincannon
Guy Kibbee character Capt. Dr. Wilkens
Grant Withers character Silas Meacham
Jack Pennick character Sgt. Daniel Schattuck
Ray Hyke character Lt. Gates
Movita character Guadalupe
Miguel Inclán character Cochise
Mary Gordon character Ma (barmaid)
Philip Kieffer character Cavalryman
Mae Marsh character Mrs. Gates
Hank Worden character Southern Recruit
John Agar character 2nd Lt. Michael Shannon O'Rourke
Abdullah Abbas character Officer at Dance (uncredited)
Danny Borzage character Recruit With Mustache / Accordionist at Serenade (uncredited)
Cliff Clark character Stage Driver (uncredited)
Jane Crowley character Officer's Wife (uncredited)
Frank Ferguson character Newspaperman (uncredited)
Francis Ford character Fen - Stage Guard (uncredited)
William Forrest character Reporter (uncredited)
Fred Graham character Cavalryman (uncredited)
Frank McGrath character Cpl. Derice (uncredited)
Clyde McLeod character Officer at Dance (uncredited)
Russell Meeker character Officer at Dance (uncredited)
Al Murphy character Orchestra Leader (uncredited)
John Rice character Officer at Dance (uncredited)
Phil Schumacher character Soldier (uncredited)
Allen D. Sewall character Officer at Dance (uncredited)
Mickey Simpson character NCO at Dance (uncredited)
Leslie Sketchley character Officer at Dance (uncredited)
Brick Sullivan character Officer at Dance (uncredited)
Harry Tenbrook character Tom O'Feeney (uncredited)
Archie Twitchell character Reporter (uncredited)
Eleanore Vogel character Officer's Wife (uncredited)
Bobby Hale character Officer at Dance