Patricia Clarkson character Mia
Rosario Dawson character Lili
Lyndsy Fonseca character Cheyanne
Ginnifer Goodwin character Charlotte
Jeanne Tripplehorn character Pearl
Emily Skinner character Sally
Carla Gallo character Laura
Aisha Hinds character Bernice
Josh Holloway character Bill
Jennifer Morrison character Sheila
Austin Nichols character Edward
Annie Potts character Helen
Xander Berkeley character Peter
Kathy Najimy character Rocky
Romy Rosemont character Lynne
Tony Shalhoub character Mitch
Jenifer Lewis character Maggie
Tracee Ellis Ross character Alyssa
Jeffrey Tambor character Danny
David Eigenberg character Lenny
Taylor Kinney character Tommy
Bob Newhart character Dr. Roth
Ravi Patel character Dr. Desai
Alan Ruck character Sam Jarente
Scott Wilson character Bill (Older)
Kirk Baily character Scott
Israel Sáez de Miguel character Dimitri
Ava Acres character Pearl at age 7
Josh Dallas character Henry
