Kate Beckinsale character Selene
Stephen Rea character Dr. Jacob Lane
Michael Ealy character Detective Sebastian
Theo James character David
India Eisley character Eve
Charles Dance character Thomas
Sandrine Holt character Lida
Sanny van Heteren character British newscaster
Jacob Blair character Kolb (Officer)
Robert Lawrenson character Waterfront Cop
Kurt Max Runte character Leader of the Troop
Marvin Duerkholz character Lestroy
Ron Wear character Jack Fletcher
Richard Cetrone character Lycan 1
Dan Payne character Lycan 2
Mark Gibbon character Announcing Guard
Benita Ha character Surgical Nurse
Tyler McClendon character Scientist
Panou character Old City Cop #1
Ian Rozylo character Old City Cop #2
Kristen Holden-Ried character Quint Lane
John Innes character Medical Supervisor
Lee Majdoub character Desk Guard
Catlin Adams character Olivia
Adam Greydon Reid character Med Tech
Christian Tessier character Security Guard #1
Wes Bentley character Antigen Scientist (uncredited)
Scott Speedman character Michael (archive footage) (uncredited)
Sanny van Heteren character BBC Announcer (uncredited)
Joe Censoplano character Cadillac Driver (uncredited)
Preston Cook character Antigen Surgeon (uncredited)
