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Dustin Hoffman character Michael Dorsey / Dorothy Michaels
Jessica Lange character Julie Nichols
Teri Garr character Sandy
Dabney Coleman character Ron Carlisle
Charles Durning character Les Nichols
Bill Murray character Jeff Slater
Sydney Pollack character George Fields
George Gaynes character John Van Horn
Geena Davis character April
Doris Belack character Rita
Ellen Foley character Jacqui
Peter Gatto character Rick
Lynne Thigpen character Jo
Ronald L. Schwary character Phil Weintraub
Debra Mooney character Mrs. Mallory
Amy Lawrence character Amy
Kenny Sinclair character Boy
Susan Merson character Page
Robert D. Wilson character Stage Hand
James Carruthers character Middle-Aged Man
Estelle Getty character Middle-Aged Woman
Christine Ebersole character Linda
Bernie Pollack character Actor #1
Sam Stoneburner character Actor #2
Marjorie Lovett character Salesgirl
Barbara Spiegel character Billie
Suzanne von Schaack character Party girl
Anne Shropshire character Mrs. Crawley
Murray Schisgal character Party guest
Richard Whiting character Priest
Jim Jansen character Stage Manager #2
Tom Mardirosian character Stage Manager
Gavin Reed character Director
Annie Korzen character Autograph Hound
Ibbits Warriner character Autograph Hound
Lois de Banzie character Autograph Hound
Stephen Prutting character Autograph Hound
Tobin Bell character Waiter (uncredited)
Phillip Borsos character (uncredited)
Jim Dratfield character Acting Student (uncredited)
John Kapelos character Actor at Party (uncredited)
Joyce Worsley character Shocked Bystander as Dorothy Grabs a Cab (uncredited)
Andy Warhol character Himself (uncredited)
Pamela Lincoln character Secretary
Michael M. Ryan character Middle-Aged Man