Paul Rudd character Pete
Leslie Mann character Debbie
Jason Segel character Jason
Maude Apatow character Sadie
Megan Fox character Desi
Lena Dunham character Cat
Melissa McCarthy character Catherine
Charlyne Yi character Jodi
John Lithgow character Oliver
Robert Smigel character CAt
Albert Brooks character Larry
Chris O'Dowd character Ronnie
Annie Mumolo character Barb
Billie Joe Armstrong character Billie Joe Armstrong
Iris Apatow character Charlotte
Michael Ian Black character Accountant
Wyatt Russell character Flirty Hockey Player
Tom Yi character Charlotte's Teacher
Tim Bagley character Dr. Pellegrino
Ava Sambora character Wendy
Graham Parker character Graham Parker
Megan Grano character School Playdate Parent
Derek Basco character Room Service Waiter
Nicol Paone character E.R. Nurse
Lynne Alana Delaney character Disturbed Restaurant Patron (uncredited)
Katia Kieling character BBQ Guest (uncredited)
Bill Hader character Desi's Store Pickup (uncredited)
Tom Everett character Pete's Doctor
Lisa Darr character Clair
Tatum O'Neal character Realtor
Ryan Adams character Ryan Adams
