Anna Faris character Cindy Campbell
Pamela Anderson character Becca
Jenny McCarthy character Kate
Marny Eng character Tabitha
Charlie Sheen character Tom
Simon Rex character George
Jianna Ballard character Sue
Jeremy Piven character Ross Giggins
Timothy Stack character Carson Ward
Elaine Klimaszewski character Elaine
Diane Klimaszewski character Diane
Camryn Manheim character Trooper Champlin
Regina Hall character Brenda Meeks
Drew Mikuska character Cody
Darrell Hammond character Father Muldoon
Anthony Anderson character Mahalik
Dexter Bell character Toilet Guy
Kevin Hart character CJ
Dame Lee character Rapper #1
Doron Bell character Rapper #2
Simon Cowell character Himself
Fat Joe character Himself
Ajay Naidu character Sayaman
Denise Richards character Annie
William S. Taylor character Mr. Meeks
Patricia Idlette character Mrs. Meeks
David Edwards character Ralph
Frank C. Turner character Mr. Meek's Brother
Monica Dillon character Brenda's Grandmother
Lori Stewart character Tabitha's Mother
Jim Bremner character Guy in Chair
Phil Dornfeld character Tabitha's Voice (voice)
Queen Latifah character Aunt Shaneequa/The Oracle
Eddie Griffin character Orpheus
Edward Moss character MJ
Dee Jay Jackson character Zubie
Leslie Nielsen character President Baxter Harris
D. L. Hughley character John Wilson
Ja Rule character Agent Thompson
George Carlin character The Architect
Master P character Himself
Macy Gray character Herself
Redman character Himself
Method Man character Himself
Raekwon character Himself
RZA character Himself
U-God character Himself
Debbie Lee Carrington character Mini Tabitha
Troy Yorke character Alien #1
Marco Soriano character Alien #2
Cliff Solomon character Native American #1
Byron Chief-Moon character Native American #2
Dolly Madsen character Native American #3
John Hainsworth character Tracheotomy Man
Beverley Breuer character Tracheotomy Wife
Jessie Young character Girl Scout
Deanne Henry character Tammy Fae Baker
Eric Breker character Secret Serviceman Jones
Naomi Lawson-Baird character Sweet Tabitha
Abigail Adams character Wedding Guest
