Simon Baker character Roderick Blank
Winona Ryder character Death Nell
Julie Bowen character Fiona Wormwood (#29)
Leslie Bibb character Dr. Miranda Storm
Skyler James Sandak character Roderick Blank Jr.
Natassia Malthe character Bambi
Jessica Kiper character Precious / Carlotta Valdes (#30)
Candice Coke character Greta Samsa (#32)
Pollyanna McIntosh character Thumper (#64)
Christopher Stapleton character Terry Fenchel (#71)
Retta character Ethel Walters (#100)
Corinne Reilly character Lizzie
Amanda Walsh character Stewardess Kathleen
Robert Wisdom character Alpha
Tanc Sade character Beta
Patton Oswalt character Fred
Dash Mihok character Lester
Neil Flynn character Zack
Indira Varma character Devon Sever
Sophie Monk character Cynthia Rose (#31)
Cindy Pickett character Roderick's Mother
Winter Ave Zoli character Alexis De Large (#37)
Bryan Okes character Buzzkilling Bodyguard
Frances Fisher character Hope Hartlight (#80)
Zachary Gordon character Barbecue Brat
