Will Forte character Shaggy Rogers (voice)
Mark Wahlberg character Blue Falcon (voice)
Jason Isaacs character Dick Dastardly (voice)
Gina Rodriguez character Velma Dinkley (voice)
Zac Efron character Fred Jones (voice)
Amanda Seyfried character Daphne Blake (voice)
Kiersey Clemons character Dee Dee Skyes (voice)
Ken Jeong character Dynomutt, Dog Wonder (voice)
Tracy Morgan character Captain Caveman (voice)
Frank Welker character Scooby-Doo / Pterodactyl (voice)
Iain Armitage character Young Shaggy (voice)
Mckenna Grace character Young Daphne (voice)
Pierce Gagnon character Young Fred (voice)
Ariana Greenblatt character Young Velma (voice)
Simon Cowell character Himself (voice)
Christina Hendricks character Officer Jaffe (voice)
Henry Winkler character Keith (voice)
Harry Perry character Himself (voice)
John DiMaggio character Restaurant Owner (voice)
Kevin Heffernan character Bike Cop Gary (voice)
Ira Glass character Himself (voice)
Henry Kaufman character Chad / Chet (voice)
Maya Erskine character Judy Takamoto (voice)
Billy West character Muttley (voice)
Don Messick character Muttley (archive audio) (voice)
Fred Tatasciore character Cerberus (voice)
Justina Machado character Jamie Rivera (voice)
Kennedy Peil character Indira Knight (voice)
John McDaniel character Hal Murphy (voice)
Ryan Folsey character Beach Guy (voice)
Pam Coats character Mrs. Rogers (voice)
Tony Cervone character Ghost / Mr. Rigby / Alice (voice)
Adam Sztykiel character Officer Casey (voice)
Alex Kauffman character Officer North (voice)
Vanara Taing character Baby Rotten (voice)
Sarah Lancia character Dispatcher Stevens (voice)
Maven Morgan character Kari (voice)
Eric Cowell character Ben (voice)
Michael Kurinsky character Samuel Colton (voice)
