Milla Jovovich character Alice
Sienna Guillory character Jill Valentine
Oded Fehr character Carlos Olivera
Thomas Kretschmann character Major Cain
Sophie Vavasseur character Angie Ashford
Razaaq Adoti character Sgt. Peyton Wells
Jared Harris character Dr. Ashford
Mike Epps character L.J.
Sandrine Holt character Terri Morales
Matthew G. Taylor character Nemesis
Zack Ward character Nicholai Ginovaeff
Iain Glen character Dr. Isaacs
Dave Nichols character Captain Henderson
Stefan Hayes character Yuri Loginova
Geoffrey Pounsett character Mackenzie
Shaun Austin-Olsen character Priest
Geny Walters character Mrs. Priest
Megan Fahlenbock character Marla Mapes
Robert Morelli character Director
Aaron Abrams character Assistant
Chris Benson character Lance Halloran
Martin Martinuzzi character Overworked Detective
Brad Borbridge character Overworked Sergeant
Frank Chiesurin character Sniper
Ron Benjamin character Bum
Kevin Hare character Home Owner / Scientist
Heather Dick character Older Woman
Alex Courey character Suit #1
John Detoro character Suit #2
Billy Khoury character Suit #3
Sava Drayton character Suit #4
Nicole Ann St. Hill character Undead Gaudy Hooker
Ricardo Betancourt character Burly Cop #1
Ted Ludzik character Burly Cop #2
Michelle Latimer character Tech #1
Catherine Burdon character Tech #2
Rebecca Sims character Undead Little Girl
Christopher Weedon character Undead Little Boy #1
Billy Parrott character Security Guard
Derek Aasland character Featured Graveyard Undead 1 (as Derek Asland) / Featured "Surplus" Undead #3
Richard Harte character Featured Graveyard Undead 2 / Featured Rooftop Undead #2
Simon Girard character Chopper Pilot #1
Dean Copkov character Chopper Pilot #2
Jeff White character Chopper Pilot #4
Tim Burd character Refugee #1
Natalie Charles character Refugee #2
Pierre Henry character Screaming Soldier
Jim Codrington character Lieutenant
Deborah Valente character Tech
Malcolm Fiddick character Reflection Undead
Malcolm Xerxes character Featured City Hall Undead #1
Michy Gustavia character Featured City Hall Undead #2
Shane Mackinnon character Featured City Hall Undead #3
Ed Fielding character Featured City Hall Undead #4
Stephen R. Hart character Featured City Hall Undead #5
Sandi Stahlbrand character Reporter #1
Christopher Marren character Guard
Tom Gerhardt character Zombie Dad
Amber Marshall character Daughter
Venice Grant character Undead Stripper #1
Ana Danilina character Undead Stripper #2
Ingrid Johansson character Featured IV Woman Undead
Jeffrey Weedon character Undead Little Boy #2
Melanie Tonello character Featured Undead Kid #1
Annabel Chu character Featured Undead Kid #2
Joey Jefferson character Featured Undead Kid #3
Heather Braaten character Featured Rooftop Undead #1
Joey Beck character Featured Rooftop Undead #3
Eric Morgan character Featured Undead City Walker #1
Gene Pyrz character Featured Undead City Walker #2
Torquil Colbo character Featured Undead City Walker #3
Joan Moore character Featured Undead City Walker #4
Peter C. Wylde character Featured Undead City Walker #5
Garry Geddes character Featured Undead City Walker #6
Dionne Renee character Featured Undead City Walker #7
Janessa Crimi character Featured Undead Kid #4
Dan Ellery character Featured Graveyard Undead 1
Sharon Moore character Featured "Surplus" Undead #2
Jo Chim character Network Anchor #1
Bobby Prochaska character Network Anchor #2
Jazz Mann character Reporter #2
Larissa Gomes character Reporter #3
Gregory White character Lab Technician
Roman Podhora character Leader Umbrella Guard
Brian King character Umbrella Gate Guard
Rob Hall character Featured School Undead
John Migliore character Zombie (uncredited)
Eric Mabius character Matt Addison (archive footage)
Liz May Brice character (archive footage)
Pasquale Aleardi character (archive footage)
Michelle Rodriguez character (archive footage)
