Ellen Burstyn character Sara Goldfarb
Jared Leto character Harry Goldfarb
Jennifer Connelly character Marion Silver
Marlon Wayans character Tyrone C. Love
Christopher McDonald character Tappy Tibbons
Keith David character Big Tim
Louise Lasser character Ada
Marcia Jean Kurtz character Rae
Janet Sarno character Mrs. Pearlman
Suzanne Shepherd character Mrs. Scarlini
Joanne Gordon character Mrs. Ovadia
Charlotte Aronofsky character Mrs. Miles
Mark Margolis character Mr. Rabinowitz
Michael Kaycheck character Donut Cop
Peter Maloney character Dr. Pill
Denise Dowse character Tyrone's Mother
Olga Merediz character Malin & Block Secretary
Ben Shenkman character Dr. Spencer
Dylan Baker character Southern Doctor
Bill Buell character Court Doctor
Lianna Pai character Angelic Nurse
Stanley B. Herman character Uncle Hank
Gregg Bello character E.R. Doctor
Shaun O'Hagan character Ward Attendant Seto
Jimmie Ray Weeks character Prison Guard
Jack O'Connell character Corn Dog Stand Boss
Chas Mastin character Lyle Russel
Ajay Naidu character Mailman
Sean Gullette character Arnold the Shrink
Samia Shoaib character Nurse Mall
Abraham Abraham character King Neptune
Aliya Campbell character Alice
Te'ron A. O'Neal character Young Tyrone
Bryan Chattoo character Brody
Eddie De Harp character Brody's Henchman Victor
Scott Franklin character Voice of Jailer (voice)
Peter Cheyenne character Sal the Geep
Brian Costello character First AD
Abraham Aronofsky character Newspaper Man on Train
James Chinlund character Space Oddity
Allison Furman character Malin & Block Office Woman
Robert Dylan Cohen character Paramedic Greenhill
Leland Gantt character Ward Attendant Penn
Henry Stram character ECT Technician
Hubert Selby Jr. character Laughing Guard
Heather Litteer character Big Tim Party Girl
Jenny Decker character Big Tim Party Girl
Ami Goodheart character Big Tim Party Girl
Nina Zavarin character Big Tim Party Girl
Scott Bader character Party Animal
Jim Centofanti character Party Animal
Scott Chait character Party Animal
Daniel Clarin character Party Animal
Ben Cohen character Party Animal
Eric Cohen character Party Animal
Brett Feinstein character Party Animal
Ricky Fier character Party Animal
John Getz character Party Animal
Andrew Kessler character Party Animal
Ross Lombardo character Party Animal
Carter Mansbach character Party Animal
Scott Miller character Party Animal
Todd Miller character Party Animal
Joshua Pollack character Party Animal
Craig Rallo character Party Animal
Geordan Reisner character Party Animal
Keith Scandore character Party Animal
David Seltzer character Party Animal
Chris Varvaro character Party Animal
Ricardo Viñas character Party Animal
Chad Weiner character Party Animal
Jesse Weissberger character Party Animal
Greg Weissman character Party Animal
Darren Aronofsky character Visitor (uncredited)
