Robert De Niro character Jackie Burke
Leslie Mann character Harmony Schiltz
Danny DeVito character Jimmy Berkowitz
Edie Falco character Miller
Harvey Keitel character Mac Schiltz
Charles Grodin character Dick D'Angelo
Patti LuPone character Florence Berkowitz
Cloris Leachman character May Conner
Veronica Ferres character Karola
Lois Smith character Miriam
Billy Crystal character Billy Crystal
Lucy DeVito character Brittany Berkowitz
Jim Norton character Jim Norton
Jimmie Walker character Jimmie Walker
Brett Butler character Brett Butler
Jessica Kirson character Jessica Kirson
Freddie Roman character Freddie Roman
Stewie Stone character Stewie Stone
Gilbert Gottfried character Gilbert Gottfried
Greer Barnes character Greer Barnes
Hannibal Buress character Hannibal Buress
Bill Boggs character Bill Boggs
Sheng Wang character Sheng Wang
Ryan Hamilton character Ryan Hamilton
Aida Rodríguez character Aida Rodriguez
Dov Davidoff character Dov Davidoff
Nick Di Paolo character Nick Di Paolo
Rebecca Kling character Heckler's Girlfriend
Jack Ricardo Miller character Homeless Man
Estee Adoram character Comedy Cellar Manager (uncredited)
Brooke Alexandra character Wedding Party (uncredited)
Happy Anderson character Heckler / Severin (uncredited)
Mark Axelowitz character Bartender at Friars Club (uncredited)
Aaron Ayhan character Lawyer (uncredited)
Marc Bicking character Spark's Maitre d' (uncredited)
Michael Birnberg character Steakhouse Customer (uncredited)
Susan Blackwell character Arlene (uncredited)
Marylouise Burke character Adele (uncredited)
José Báez character Homeless (uncredited)
Craig 'Radioman' Castaldo character Soup kitchen - patron 1 (uncredited)
Lyman Chen character Chinese Waiter (uncredited)
Teddy Coluca character Fan (uncredited)
Stephanie Corbett character Bayou Babe (uncredited)
Savvy Crawford character The kid (uncredited)
Ray Crisara character Gary (uncredited)
Barbara Danicka character Stenographer (uncredited)
Barbara Ann Davison character Fan at Convention (uncredited)
Karin de la Penha character Woman on Train (uncredited)
Kevin Dohrenwend character Prison Inmate (uncredited)
Michael-Scott Druckenmiller character Floridian Parent (uncredited)
Sarah Fearon character Friars Club Member (uncredited)
Michael Fischetti character Older man (uncredited)
Abigail Friend character Wedding Guest (uncredited)
