Ron Perlman character Brother Samuel
Thomas Jane character Maj. 'Mitch' Hunter
Devon Aoki character Cpl. Valerie Duval
Sean Pertwee character Capt. Nathan Rooker
Benno Fürmann character Lt. Maximillian von Steiner
John Malkovich character Constantine
Anna Walton character Severian
Tom Wu character Cpl. Juba Kim Wu
Steve Toussaint character Capt. John McGuire
Luis Echegaray character Cpl. Jesus 'El Jesus' de Barrera
Pras Michel character Captain Michaels
Shauna Macdonald character Adelaide
Roger Ashton-Griffiths character Science Monk
Christopher Adamson character Hodge
Jacqueline Chan character Mishima Ambassador (as Jacqui Chan)
Nicholas Ball character Plutocrat
Georgina Berriman character Grace
Georgina Bryce character Dorothy
Richard Buddle character Soldier
Tim Daniel Clark character Lead Mutant
Vyelle Croom character Bartender
Barry McCormick character Capitol Ambassador
Scott Joseph character Corporate Guard
Farhan Khan character Principal Mutant
Andrew Mackay character Science Monk's Assistant
Tatiana Lavrentieva character Refugee (uncredited)
Albert Tang character Japanese General (uncredited)