Matthew McConaughey character Ed 'Eddie' Pekurny
Woody Harrelson character Ray Pekurny
Sally Kirkland character Jeanette
Jenna Elfman character Shari
Martin Landau character Al
Ellen DeGeneres character Cynthia Topping
Rob Reiner character Mr. Whitaker
Dennis Hopper character Henry 'Hank' Pekurny
Elizabeth Hurley character Jill
Adam Goldberg character John
Viveka Davis character Marcia
Clint Howard character Ken
Geoffrey Blake character Keith
Gail Boggs character Wife
Jenna Byrne character Felicia
Greg Sestero character Roach
RuPaul character RuPaul
Merrin Dungey character Ms. Seaver
Ian Gomez character McIlvaine
Gavin Grazer character Clint
Chris Hogan character Paul
Arianna Huffington character Panel Member
Larry "Flash" Jenkins character Husband
Wendle Josepher character Rita
Scott LaRose character Desipio
John Livingston character Terry
Mitzi McCall character Fig Lady
Jim Meskimen character Dr. Geller
Don Most character Benson
Rick Overton character Barry
James Ritz character Tad
Rusty Schwimmer character Alice
Steven Shenbaum character Jack
Gedde Watanabe character Greg
Steve Kehela character Reporter
Googy Gress character Reporter
Jo McGinley character Tracy
John Pirruccello character Kevin
Charles Arthur Berg character Party Goer
Anthony Jensen character Party Goer
Sommer Garcia character College Girl
Jennifer Elise Cox character College Girl
Alexandra Holden character College Girl
Mark Wheeler character Bartender
Anna Karin character Snapple Girl
George Plimpton character Panel Member
Michael Moore character Panel Member
Merrill Markoe character Panel Member
Bill Maher character Bill Maher
Jay Leno character Jay Leno
Sonia Bhalla character Ticket Taker
Joe Bellan character Lou
Diane Amos character Autograph Mom
Wade Robson character Teenage Boy
Andy Arness character Groupie (uncredited)
Cyndi Pass character Cassie
J. Anthony Pena character Con-Ed Guy (uncredited)
Carl Solomon character Ed Groupie (uncredited)