Zachary Levi character Toby
David Cross character Ian
Jason Lee character Dave
Justin Long character Alvin (voice)
Matthew Gray Gubler character Simon (voice)
Jesse McCartney character Theodore (voice)
Amy Poehler character Eleanor (voice)
Anna Faris character Jeanette (voice)
Christina Applegate character Brittany (voice)
Wendie Malick character Dr. Rubin
Anjelah Johnson-Reyes character Julie
Kathryn Joosten character Aunt Jackie
Kevin Schmidt character Ryan
Chris Warren character Xander
Bridgit Mendler character Becca
Aimee Carrero character Emily
Alexandra Shipp character Valentina
Gregg Binkley character Emcee
Jake Zyrus character Charice Pempengco
Bernard White character Doctor
Adele Jacques character Nurse
Joy Osmanski character Airline Rep
Archie Hahn character Agent
Lanny Joon character Paramedic
Brando Eaton character Jeremy
Michael Bruno character Honor Society
Andrew Lee Schmidt character Honor Society
Alexander Noyes character Honor Society
Jason Rosen character Honor Society
Ali Mikles character Screaming Fan
Eric Bauza character Digger the NASCAR Gopher (voice)
Sean Astin character Meerkat Manor Narrator (voice)
Marty Dew character Chipmunk Dancer
Richy Jackson character Chipmunk Dancer
Mihran Kirakosian character Chipmunk Dancer
Janelle Ginestra character Chipette Dancer
Thomasina Gross character Chipette Dancer
Rachele Brooke Smith character Chipette Dancer
Ryan Conferido character Li'l Rosero Dancer
Hokuto 'Hok' Konishi character Li'l Rosero Dancer
Ryan Feng character Li'l Rosero Dancer
Dominic Sandoval character Li'l Rosero Dancer
Brian Hirano character Li'l Rosero Dancer
Steve Terada character Li'l Rosero Dancer
Victor Kim character Li'l Rosero Dancer
Brittany Anne Pirtle character Cheerleader (uncredited)
Ross Bagdasarian, Jr. character Alvin (singing voice) (uncredited)
Janice Karman character Theodore / The Chipettes (singing voice) (uncredited)
Steve Vining character Simon (singing voice) (uncredited)
Courtney Platt character Eleanor - Performer (voice) (uncredited)
Gee Alexander character Simon Dance Double (uncredited)
Mark Alkofer character Football Referee (uncredited)
Tallie Brinson character Principal Dancer (uncredited)
Ericka Clevenger character Cheerleader (uncredited)
Sean Decker character Dodgeball Player (uncredited)
Sarah Fontenot character Cheerleader (uncredited)
Paul Gonzales character Charice Bassist (uncredited)
David Lautman character High School Student (uncredited)
Casper Smart character Dancer (uncredited)
Andrew Thompson character Stadium Announcer (uncredited)
