Jim Carrey character Lloyd Christmas
Jeff Daniels character Harry Dunne
Rachel Melvin character Penny
Kathleen Turner character Fraida
Rob Riggle character Travis / Captain Lippincott
Laurie Holden character Adele
Tembi Locke character Dr. Walcott
Paul Blackthorne character Emergency Room Doctor
Gregory Fears character Man at Gas Station
Brady Bluhm character Billy
Patricia French character Ms. Sourpuss
Steve Tom character Dr. Pinchelow
Don Lake character Dr. Meldman
Eddie Shin character Gordy
Atkins Estimond character Gus
Tommy Snider character Tom
Lindsay Ayliffe character Professor Garabedian
Matthew Cardarople character Inventor No. 1
Bill Murray character Ice Pick
Grant James character Mr. Stainer
Taylor St. Clair character Mrs. Steiner
Erin Allin O'Reilly character Asylum Nurse No. 1
Walt Arnett character KEN Audience Member
Erika Bierman character Fanny at Age 13
Kassidy Claire character Fanny at Age 5
Carly Craig character Young Fraida
Bryan Dilbeck character Dr. Dilbeck
Dalton E. Gray character Young Harry
Michael McCrudden character Audience Member
June Shannon character Harry's Trailer Park Wife
Maia Moss-Fife character Receptionist
Jeff Sumner character Convention Official
Julius Sharpe character KEN Conference Attendee
Dave Walpole character KEN Conference Attendee
Brett Wyman character Inventor No. 2
Paul Bednarz character KEN Convention Employee (uncredited)
Jennifer Cocker character Young Inventor (uncredited)
John Deifer character Mental Patient (uncredited)
Abigail Gamache character Prom Attendee (uncredited)
William Goodrum character Prom Singer (uncredited)
Walter Hendrix III character Street Patron (uncredited)
Angela Kerecz character Waitress (uncredited)
John Merical character Neighbor (uncredited)
Elizabeth Cooper character Mrs. Julie James
Michael Yama character Harry's Dad
Nancy Yee character Harry's Mom
Nancy Byers Farrelly character Asylum Nurse #2
Derek Holland character Asylum Patient
Brendan Boyle character Asylum Patient
Swizz Beatz character Ninja Leader
Mike Cerrone character Trucker
Sean Gildea character Trucker's Pal
Kassidy Claire character Fanny Age 5
Brett Wyman character Inventor #2
Jo Helton character Mrs. Snergle
Erika Bierman character Fanny Age 13
Edward Barbanell character Nursing Home Orderly
Mariann Neary character Farmer's Wife
John Imlay character Farmer
Jon Barinholtz character Inventor No. 3
Lucas Daniels character Bartender
Carter Hicks character Bus Kid
Baxter Cooper Rogers character Prom Date
Sandra Dorsey character Stuffy Woman
Arielle Liberman character Emergency Room Nurse
Jon Barry character Emergency Room Orderly
Jesse Gines character Emergency Room Orderly
Robin O'Neal Sorensen character Emergency Medical Technician #1
Chris Randall Sorensen character Emergency Medical Technician #2
Daniel Greene character Wheelchair Ninja
Will Coogan character Room Service Waiter
Caryle Seim character Trailer Grandma
Danny Murphy character Joystick Victim
Rhomyen Johnson character Bus Driver
