Nicole Kidman character Isabel Bigelow
Will Ferrell character Jack Wyatt
Shirley MacLaine character Iris Smythson / Endora
Michael Caine character Nigel Bigelow
Jason Schwartzman character Ritchie
Kristin Chenoweth character Maria Kelly
Heather Burns character Nina
Jim Turner character Larry
Stephen Colbert character Stu Robison
David Alan Grier character Jim Fields
Michael Badalucco character Joey Props
Carole Shelley character Aunt Clara
Steve Carell character Uncle Arthur
Katie Finneran character Sheila Wyatt
James Lipton character Himself
Conan O'Brien character Conan O'Brien
Amy Sedaris character Gladys Kravitz
Richard Kind character Abner Kravitz
Ken Hudson Campbell character Writer
P. J. Byrne character Writer
Carole Androsky character Realtor
Annie Mumolo character Bed, Bath and Beyond Shopper
Andrew Friedman character Bed, Bath and Beyond Shopper
Clay Bravo character Coffee Shop Waitress
Heather Maristella character Beverly Hills Hotel Hostess
Jonathan T. Floyd character Cable Man
Ed McMahon character Ed McMahon
Alison MacInnis character Auditioning Actress
Bridget Brno character Auditioning Actress
Dana Daurey character Auditioning Actress
Dorie Barton character Auditioning Actress
Katie Carroll character Auditioning Actress
Jennifer Elise Cox character Auditioning Actress
Laura Sorenson character Auditioning Actress
Brittany Krall character Auditioning Actress
Dawn Ashley Cook character Auditioning Actress
Julia Decker character Auditioning Actress
Abbey McBride character Auditioning Actress
Jennifer Hall character Book Soup Cafe Waitress
Roxanne Beckford character Francine
Hugh Davidson character Network Executive
Joe Zymblosky character Randall
J.J. Sacha character Voice-Over Announcer
Susan Chuang character Press Conference Reporter
Jordan Black character Press Conference Photographer
Mo Rocca character E! Reporter
Jason George character E! Anchor
Wendi McLendon-Covey character E! Anchor
Julie Claire character Hillary
Terry Savage character Dinner Party Guest
Dianne Dreyer character Production Staff Assistant
Kate Walsh character Sexy Waitress
Valerie Azlynn character Gorgeous Model
Jarrad Paul character Valet
Victor Williams character Police Officer
Liesel Staubitz character Trick-or-Treater
Ruby Rose Skotchdopole character Trick-or-Treater
Molly Gordon character Trick-or-Treater
Nick Lachey character Vietnam Soldier