Philip Seymour Hoffman character Andy Hanson
Ethan Hawke character Hank Hanson
Albert Finney character Charles Hanson
Marisa Tomei character Gina Hanson
Aleksa Palladino character Chris Lasorda
Michael Shannon character Dex
Amy Ryan character Martha Hanson
Sarah Livingston character Danielle
Brían F. O'Byrne character Bobby Lasorda
Rosemary Harris character Nanette Hanson
Blaine Horton character Justin
Arija Bareikis character Kathrine
Leonardo Cimino character William
Lee Wilkof character Jake
Damon Gupton character Doctor
Myra Lucretia Taylor character Grader
Marcia Jean Kurtz character Hotel Receptionist
Adrian Martinez character Security Guard
Patrick G. Burns character Priest
Alice Spivak character Receptionist
Natalie Gold character Secretary
Keith Davis character Attendant
Mateo Gómez character Doorman (as Mateo Gomez)
Chris Chalk character Officer
Sakina Jaffrey character Manager
John Knox character Desk Sergeant
James Lally character Agent
Jordan Gelber character Agent #2
Megan Byrne character Nurse
Guy A. Fortt character Vendor
Meredith Patterson character Andy's Secretary
Tom Zolandz character Junkie
Paul Butler character Detective
Anita Sklar character Mourner #1
Josh Mowery character Mourner #2
Diane Bradley character Mourner #3
Richard Lublin character Mourner #4 (as Richard K. Lublin)
Bob Colletti character Ambulance Driver
Mary DeBellis character Mall Shopper (uncredited)
Alex Emanuel character Bartender (uncredited)
Jack Fitz character Katherine's Husband (uncredited)
Zeke Hawkins character Hospital Guest (uncredited)
Charles Kopelson character Drunk at Bar (uncredited)
Denis McKeown character Mourner (uncredited)
Nicholas E. Pagani character Taxi Driver (uncredited)