Roy Scheider character Dr. Heywood Floyd
John Lithgow character Dr. Walter Curnow
Helen Mirren character Tanya Kirbuk
Bob Balaban character Dr. R. Chandra
Keir Dullea character Dave Bowman
Douglas Rain character HAL 9000
Madolyn Smith Osborne character Caroline Floyd
Savely Kramarov character Dr. Vladimir Rudenko
Taliesin Jaffe character Christopher Floyd
James McEachin character Victor Milson
Mary Jo Deschanel character Betty Fernandez
Elya Baskin character Maxim Brailovsky
Dana Elcar character Dimitri Moisevitch
Oleg Rudnik character Dr. Vasili Orlov
Natasha Shneider character Irina Yakunina
Vladimir Skomarovsky character Yuri Svetlanov
Victor Steinbach character Nikolaj Ternovsky
Candice Bergen character SAL 9000
Gene McGarr character Commercial Announcer
