Keir Dullea character Dr. David Bowman
Gary Lockwood character Dr. Frank Poole
William Sylvester character Dr. Heywood Floyd
Douglas Rain character HAL 9000 (voice)
Daniel Richter character Moonwatcher
Leonard Rossiter character Dr. Andrei Smyslov
Margaret Tyzack character Elena
Robert Beatty character Dr. Ralph Halvorsen
Sean Sullivan character Dr. Roy Michaels
Frank Miller character Mission Controller
Ed Bishop character Aries-1B Lunar Shuttle Captain
Edwina Carroll character Aries-1B Stewardess
Heather Downham character Stewardess
Penny Brahms character Stewardess
Maggie d'Abo character Stewardess
Chela Matthison character Stewardess
Judy Kiern character Voiceprint Identification Girl
Alan Gifford character Poole's Father
Ann Gillis character Poole's Mother
Vivian Kubrick character Floyd's daughter (uncredited)
Kenneth Kendall character BBC-12 Announcer
Kevin Scott character Miller
Martin Amor character Interviewer Martin Amor
Bill Weston character Astronaut
Glenn Beck character Astronaut
Mike Lovell character Astronaut
John Ashley character Ape
Jimmy Bell character Ape
David Charkham character Ape
Simon Davis character Ape
Jonathan Daw character Ape
Péter Delmár character Ape
Terry Duggan character Ape Attacked by Leopard
David Fleetwood character Ape
Danny Grover character Ape
Brian Hawley character Ape
David Hines character Ape
Tony Jackson character Ape
John Jordan character Ape
Scott MacKee character Ape
Laurence Marchant character Ape
Darryl Paes character Ape
Joe Refalo character Ape
Andy Wallace character Ape
Bob Wilyman character Ape
Richard Woods character Ape Killed by Moon-Watcher
S. Newton Anderson character Young Man (uncredited)
Sheraton Blount character (uncredited)
Ann Bormann character (uncredited)
Julie Croft character (uncredited)
Penny Francis character (uncredited)
Marcella Markham character (uncredited)
Irena Marr character Russian Scientist (uncredited)
Krystyna Marr character Russian Scientist (uncredited)
Kim Neil character (uncredited)
Jane Pearl character (uncredited)
Penny Pearl character (uncredited)
Burnell Tucker character TMA-1 Site Photographer (uncredited)
John Swindells character TMA-1 Site Technician #1 (uncredited)
John Clifford character TMA-1 Site Technician #2 (uncredited)
