Chris Evans в ролята на Casey Jones (voice)
Sarah Michelle Gellar в ролята на April O'Neil (voice)
Mako в ролята на Splinter (voice)
Kevin Smith в ролята на Diner Cook (voice)
Patrick Stewart в ролята на Winters (voice)
Zhang Ziyi в ролята на Karai (voice)
Laurence Fishburne в ролята на Narrator (voice)
Mitchell Whitfield в ролята на Donatello / Additional Voices (voice)
James Arnold Taylor в ролята на Leonardo (voice)
Mikey Kelley в ролята на Michelangelo (voice)
Nolan North в ролята на Raphael / Nightwatcher (voice)
John DiMaggio в ролята на Colonel Santino (voice)
Paula Mattioli в ролята на General Serpiente (voice)
Kevin Michael Richardson в ролята на General Aguila / Additional Voices (voice)
Fred Tatasciore в ролята на General Gato / Additional Voices (voice)
Dee Bradley Baker в ролята на Additional Voices (voice)
Greg Baldwin в ролята на Additional Voices (voice)
Jeff Bennett в ролята на Additional Voices (voice)
Jim Cummings в ролята на Additional Voices (voice)
Grey DeLisle в ролята на Additional Voices (voice)
Chris Edgerly в ролята на Additional Voices (voice)
Kim Mai Guest в ролята на Additional Voices (voice)
Jennifer Hale в ролята на Additional Voices (voice)
Jess Harnell в ролята на Additional Voices (voice)
Phil LaMarr в ролята на Additional Voices (voice)
Paul Michael Robinson в ролята на Additional Voices (voice)
Tara Strong в ролята на Additional Voices (voice)
Billy West в ролята на Additional Voices (voice)
Kevin Munroe в ролята на Diner Patron (voice) (uncredited)
