Reese Witherspoon в ролята на Susan Murphy / Ginormica (voice)
Seth Rogen в ролята на B.O.B. (voice)
Hugh Laurie в ролята на Dr. Cockroach Ph.D. (voice)
Will Arnett в ролята на The Missing Link (voice)
Kiefer Sutherland в ролята на General W.R. Monger (voice)
Rainn Wilson в ролята на Gallaxhar (voice)
Paul Rudd в ролята на Derek Dietl (voice)
Stephen Colbert в ролята на President Hathaway (voice)
Jimmy Kimmel в ролята на Insectosaurus (voice)
Julie White в ролята на Wendy Murphy (voice)
Jeffrey Tambor в ролята на Carl Murphy (voice)
Amy Poehler в ролята на Computer (voice)
Ed Helms в ролята на News Reporter (voice)
Renée Zellweger в ролята на Katie (voice)
Sean Bishop в ролята на Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)
Rich Dietl в ролята на Commander / Advisor Smith (voice)
Rob Letterman в ролята на Secret Service Man #1 / Lieutenant (voice)
Tom McGrath в ролята на Wilson (voice)
Chris Miller в ролята на Advisor Cole / Army Commander Jones (voice)
Mike Mitchell в ролята на Advisor Wedgie (voice)
Kent Osborne в ролята на Technician Jerry (voice)
Latifa Ouaou в ролята на Advisor Ouaou / Mrs. Ronson / Female Advisor #2 / Panicked Guest (voice)
Geoffrey Pomeroy в ролята на Soldier #4 / Pilot / Soldier #3 / News Technician (voice)
David P. Smith в ролята на Soldier #1 / Advisor Jackson (voice)
Lisa Stewart в ролята на Bridesmaid Candy (voice)
Conrad Vernon в ролята на Advisor Hawk / Advisor Dither / Minister / Secret Service Man #2 / Mama Dietl (voice)
John Krasinski в ролята на Cuthbert (voice)
Stephen Kearin в ролята на Technician Bee (voice)
